Почему мы умираем: Передовая наука о старении и поиск бессмертия - Венки Рамакришнан

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Долгое время Макклинток не верили, но так называемые транспозоны оказались фундаментальным явлением биологии, и в 1983 г. в возрасте 81 года Барбара Макклинток была удостоена Нобелевской премии.

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Деятельность организации признана нежелательной на территории Российской Федерации. – Прим. ред.

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Более длинная нить ДНК обозначается как «3'-конец», и причина утраты теломерной ДНК не совсем та, которую сначала предположили Оловников и Уотсон. Тем, кто заинтересуется этой темой, советую прочитать статью: J. Lingner, J. P. Cooper, and T. R. Cech, "Telomerase and DNA End Replication: No Longer a Lagging Strand Problem," Science 269, no. 5230 (September 15, 1995): 1533–34, https://doi.org/10.1126/science.7545310.

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От англ. shelter – «прикрытие, защита». – Прим. ред.

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E. S. Epel et al., "Accelerated Telomere Shortening in Response to Life Stress," Proceedings of the National Academy of Sciences (PNAS) of the United States of America 101, no. 49 (December 1, 2004): 17312–15, https://doi.org/10.1073/pnas.0407162101; J. Choi, S. R. Fauce, and R. B. Effros, "Reduced Telomerase Activity in Human T Lymphocytes Exposed to Cortisol," Brain, Behavior, and Immunity 22, no. 4 (May 2008): 600–605, https://doi.org/10.1016/j.bbi.2007.12.004. О стрессе и преждевременной седине у мышей см. также: B. Zhang et al., "Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells," Nature 577, no. 792 (January 2020): 676–81, https://doi.org/10.1038/s41586–020–1935–3.

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M. A. Muñoz-Lorente, A. C. Cano-Martin, and M. A. Blasco, "Mice with Hyperlong Telomeres Show Less Metabolic Aging and Longer Lifespans," Nature Communications 10, no. 1 (October 17, 2019): 4723, https://doi.org/10.1038/s41467–019–12664-x.

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Тития де Ланге, беседы и электронная переписка с автором в ноябре и декабре 2021 г. См. также: Jalees Rehman, "Aging: Too Much Telomerase Can Be as Bad as Too Little," Guest Blog, сайт Scientific American, https://blogs.scientificamerican.com/guest-blog/aging-too-much-telomerase-can-be-as-bad-as-too-little/, дата последнего изменения 0507.2014.

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